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Hemophilia Market, By Types (Hemophilia A, Hemophilia B, and Hemophilia C), By Treatment (On-demand and Prophylaxis), By Therapy and Geography (NA, EU, APAC, and RoW) – Analysis, Share, Trends, Size, & Forecast From 2014 – 2025

120 Pages | Published Date : 10 / 04 / 18  | Report Code: AV180 | Report Format: PDF

REPORT HIGHLIGHT

The hemophilia market is estimated to represent a global market of USD 10.23 billion by 2017 with growth rate of 5.3%.

Market Dynamics

Over the eight years to 2016, revenue for the hemophilia industry is anticipated trend higher. Increasing neonatal population is expected to drive the hemophilia diagnosis demand globally. The World Population Meter stated that more than 88.0 billion newborns were reported in 2015 resulting in about 250 births per minute. Of which, approximately 2.8 million infants died within the first month, due to lack of skilled care and proper screening of the babies. The World Health Organization (WHO) also stated that around 2.6 million children died in their first month of life across the globe, which is 7,000 newborn deaths every day. In addition, strong product pipeline will further stimulate the industry growth to great extent over the future period. For example, N9-GP, Concizumab, N8-GP, and Recombinant factor VIIa are some of the bleeding disorder therapeutics under clinical investigations by Novo Nordisk. Despite the industry pipeline increasing, some potential threats exist which will likely to hinder growth prospects going forward. Factors such as high treatment cost coupled with low acceptance of advanced technologies are posing a potential threat to the market.

Types Takeaway

In terms of types, the market is categorized into A, B, C, and other types. Type A accounted for the highest share of the total market. In 2017, the segment recorded 6.8 billion and is expected to dominate the global market over the forecast period. This type is acquired due to the deficiency of clotting factor VIII, which is an anti-hemophilic factor (AHF). According to the National Hemophilia Foundation (NHF), 1 in 5,000 male population affect with type A disorder, which makes it four times more common compared to the type B. As per the Hemophilia News Today, around 4,000 to 5,000 males are affected with type A disease worldwide. Markets besides hemophilia A, B & C is expected to generate the remaining 5.0% of market revenue in 2017.

Treatment Takeaway

The treatment segment is divided into On-demand and Prophylaxis. Inpatient with mild to severe hemophilia, treatment is being given at the time when bleeding occurs which is termed as on-demand therapy. The on-demand treatment industry is in the mature phase and is projected to grow with a significant growth rate over the foreseeable future. Depending upon therapy, the market is segmented as Immune Tolerance Induction (ITI), Replacement, and Gene therapy. Replacement therapy captures a major chunk of the global revenue. This method is performed through the infusion of factor VIII and IX concentrates to prevent bleeding. On contrary, gene therapy is considered to be the lowest revenue generating segment, generated less than 1% revenue in 2017. Most of the gene therapies for hemophilia treatment are under clinical studies and likely attract greater demand during the future period.

Key Vendor Takeaway

Companies namely, Novo Nordisk, Bayer AG, Pfizer, Inc., Baxalta, and Biogen are profiled. In light of more players entering in this market. the degree of competition has intensified over a couple of years. Competition is based on the development of new therapeutics and co-pay programs.

For example, Grifols provide co-pay programs such as ALPHANATE Copay Program and AlphaNine SD Copay card for this bleeding disorder treatment with an unlimited monetary limit. In addition, companies are engaged in donation activities with government organizations. For instance, in 2016, the World Federation of Hemophilia collected 1.5 million units of anti-hemophilic agents from CSL Behring as a donation on World Hemophilia Day.

The market size and forecast for each segment and sub-segments has been considered as below:

  • Historical Year – 2014 & 2016
  • Base Year – 2017
  • Estimated Year – 2018
  • Projected Year – 2025

TARGET AUDIENCE

  • Traders, Distributors, and Suppliers
  • Manufacturers
  • Hospitals
  • Government and Regional Agencies and Research Organizations
  • Consultants
  • Distributors

SCOPE OF THE REPORT

The scope of this report covers the market by its major segments, which include as follows:

MARKET, BY TYPES

  • Hemophilia A
  • Hemophilia B
  • Hemophilia C
  • Others

MARKET, BY TREATMENT

  • On-demand
  • Prophylaxis

MARKET, BY THERAPY

  • Immune Tolerance Induction (ITI) therapy
  • Replacement therapy
  • Gene therapy

MARKET, BY REGION

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • France
    • Rest of Europe
  • Asia Pacific
    • India
    • China
    • Rest of APAC
  • Rest of the World
    • Middle East and Africa
    • Latin America
TABLE OF CONTENT

1. HEMOPHILIA MARKET OVERVIEW
1.1. Study Scope
1.2. Assumption and Methodology
2. EXECUTIVE SUMMARY
2.1. Key Market Facts
2.2. Geographical Scenario
2.3. Companies in the Market
3. HEMOPHILIA KEY MARKET TRENDS
3.1. Market Drivers
3.1.1. Impact Analysis of Market Drivers
3.2. Market Restraints
3.2.1. Impact Analysis of Market Restraints
3.3. Market Opportunities
3.4. Market Future Trends
4. HEMOPHILIA INDUSTRY STUDY
4.1. Porter’s Analysis
4.2. Market Attractiveness Analysis
4.3. Regulatory Framework Analysis
5. HEMOPHILIA MARKET LANDSCAPE
5.1. Market Share Analysis
6. HEMOPHILIA MARKET – BY TYPES
6.1. Overview
6.2. Hemophilia A
6.2.1. Overview
6.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
6.3. Hemophilia B
6.3.1. Overview
6.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
6.4. Hemophilia C
6.4.1. Overview
6.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
6.5. Others
6.5.1. Overview
6.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
7. HEMOPHILIA MARKET – BY TREATMENT
7.1. Overview
7.2. On-demand
7.2.1. Overview
7.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
7.3. Prophylaxis
7.3.1. Overview
7.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
8. HEMOPHILIA MARKET – BY THERAPY
8.1. Overview
8.2. Immune Tolerance Induction (ITI) therapy
8.2.1. Overview
8.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
8.3. Replacement therapy
8.3.1. Overview
8.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
8.4. Gene therapy
8.4.1. Overview
8.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9. HEMOPHILIA MARKET– BY GEOGRAPHY
9.1. Introduction
9.2. North America
9.2.1. Overview
9.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.2.3. U.S.
9.2.3.1. Overview
9.2.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.2.4. Canada
9.2.4.1. Overview
9.2.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.3. Europe
9.3.1. Overview
9.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.3.3. France
9.3.3.1. Overview
9.3.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.3.4. Germany
9.3.4.1. Overview
9.3.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.3.5. Rest of Europe
9.3.5.1. Overview
9.3.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.4. Asia Pacific (APAC)
9.4.1. Overview
9.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.4.3. China
9.4.3.1. Overview
9.4.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.4.4. India
9.4.4.1. Overview
9.4.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.4.5. Rest of APAC
9.4.5.1. Overview
9.4.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.5. Rest of the World
9.5.1. Overview
9.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.5.3. Latin America
9.5.3.1. Overview
9.5.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
9.5.4. Middle East and Africa
9.5.4.1. Overview
9.5.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
10. KEY VENDOR ANALYSIS
10.1. Novo Nordisk
10.1.1. Company Overview
10.1.2. SWOT Analysis
10.1.3. Key Developments
10.2. Bayer AG
10.2.1. Company Overview
10.2.2. SWOT Analysis
10.2.3. Key Developments
10.3. Pfizer, Inc.
10.3.1. Company Overview
10.3.2. SWOT Analysis
10.3.3. Key Developments
10.4. Baxalta
10.4.1. Company Overview
10.4.2. SWOT Analysis
10.4.3. Key Developments
10.5. Biogen
10.5.1. Company Overview
10.5.2. SWOT Analysis
10.5.3. Key Developments
*Client can request additional company profiling as per specific requirements
11. 360 DEGREE ANALYSTVIEW
12. APPENDIX
12.1. Research Methodology
12.2. Abbreviations
12.3. Disclaimer
12.4. Contact Us

List of Tables
Table 1 List of Acronyms
Table 2 Key Market Facts, 2014 – 2025
Table 3 Market Drivers: Impact Analysis
Table 4 Market Restraint: Impact Analysis
Table 5 Market Opportunity: Impact Analysis
Table 6 PEST Analysis
Table 7 Porter’s Five Forces Analysis
Table 8 Company Market Share Analysis
Table 9 Global Hemophilia Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Billion)
Table 10 Hemophilia Market, by Types, 2014 – 2025 (USD Billion)
Table 11 Hemophilia Market, by Treatment, 2014 – 2025 (USD Billion)
Table 12 Hemophilia Market, by Therapy, 2014 – 2025 (USD Billion)
Table 13 Hemophilia Market, by Geography, 2014 – 2025 (USD Billion)
Table 14 North America Hemophilia Market, 2014 – 2025 (USD Billion)
Table 15 U.S. Hemophilia Market, 2014 – 2025 (USD Billion)
Table 16 Canada Hemophilia Market, 2014 – 2025 (USD Billion)
Table 17 Europe Hemophilia Market, 2014 – 2025 (USD Billion)
Table 18 France Hemophilia Market, 2014 – 2025 (USD Billion)
Table 19 Germany Hemophilia Market, 2014 – 2025 (USD Billion)
Table 20 Asia Pacific Hemophilia Market, 2014 – 2025 (USD Billion)
Table 21 China Hemophilia Market, 2014 – 2025 (USD Billion)
Table 22 India Hemophilia Market, 2014 – 2025 (USD Billion)
Table 23 Latin America Hemophilia Market, 2014 – 2025 (USD Billion)
Table 24 MEA Hemophilia Market, 2014 – 2025 (USD Billion)

List of Figures
Figure 1 Research Methodology
Figure 2 Research Process Flow Chart
Figure 3 Comparative Analysis, by Geography, 2016-2025 (Value %)
Figure 4 Regulatory Framework Analysis
Figure 5 Hemophilia Market, by Types, 2014 – 2025 (USD Billion)
Figure 6 Hemophilia Market, by Treatment, 2014 – 2025 (USD Billion)
Figure 7 Hemophilia Market, by Therapy, 2014 – 2025 (USD Billion)
Figure 8 Hemophilia Market, by Geography, 2014 – 2025 (USD Billion)

SCOPE AND OBJECTIVES
The objective of this report is to describe the market trends and revenue forecasts for the market for the upcoming years. The report focuses on defining and describing the key influencing factors for the growth of the market. It also offers an in-depth analysis of the market size (revenue), market share, major market segments, different geographic regions, key market players, and premium industry trends.
The report tracks the major market events including product launches, technological developments, mergers & acquisitions, and the innovative business strategies opted by key market players. Along with strategically analysing the key micro markets, the report also focuses on industry-specific drivers, restraints, opportunities and challenges in the market. The scope of this report covers the market by its major segments.

KEY BENEFITS OF THE REPORT
• In-depth analysis of the key market dynamics
• Granular analysis of the current market scenario and expected factors to affect the market
• Detailed analysis of the geographic region, regional and county wise analysis
• Highlight on the strategies that are being adopted by the key players in this market to stay competitive
• Extensive analysis of the key players dominating the market

RESEARCH METHODOLOGY

Research methodology is developed on a combination of specialist industry analyst knowledge and in-country research experience. We employ data interrogation methodologies to generate new and meaningful analyses and insights. The research study includes extensive use of secondary sources, paid databases (such as Bloomberg, Dun & Bradstreet, and BusinessWeek) and directories, to identify and collect information, useful to understand technical, commercial and market-oriented aspects. Market data and information are also collected (but not limited to) from the secondary sources such as:

  • Official company’s website, financial and annual reporting
  • Government statistical data
  • Online publishing articles
  • Industry player’s investor presentations
  • Economic news articles
  • National and international trade associations
  • The financial, business, and mainstream press
  • Industry study groups and semiofficial sources
  • Informative channels related to the market topics

* Gathering data through secondary sources is only the first step. The ability to cross-refer market data through available secondary            information often conflicting across multiple sources is a key aspect of the added value we provide

In order to verify and validate secondary market data, we engage with the Key Opinion Leaders (KoL’s), operating in the respective markets, through phone calls, emails, and web-based survey responses. This platform help us validate our data in terms of accuracy and gain insight into the current market and future expectations. Furthermore, the obtained information guide us to understand several facets of the market with respect to manufacturers and buyers’ perspectives.

In addition, to assign weights to all the relevant market dynamics and parameters and quantify their market impact for generating projected market growth rate, we used advanced machine learning algorithms in order to collate essential market data. The machine learning method utilizes algorithms such as regression, correlation, and decision tree, among others, to derive the desired output. This tool help us in deriving highly detailed forecasts, profound knowledge of product demand, and others.

These collected data points are carefully filtered, analyzed, compared, and presented in an easy way to develop accurate research study. Furthermore, all collected data is subjected to undergo exhaustive review process at country level, regional level, and global level.

Market Forecast

Market forecast is primarily based on the year-on-year (YOY) growth rate. Data projection and future performance of each segment is analyzed based on the key aspects extracted from primary and secondary research results. Thus, data projection exhibits the assumption on how the market performs under microeconomic and macroeconomic parameters. Our market forecasting technique represents strategic conclusions which can play a crucial role for our client’s in making strategic marketing plans.

For forecasting, the following parameters were considered:

  • Market drivers and restraints along with their current and expected impacts
  • Technological scenario and expected developments
  • Trends in the consumer behaviors
  • End-user industry trends

We have assigned weights to above-mentioned parameters and quantified their market impacts using the weighted average analysis, to derive an expected market growth rate.

Market Analysis

Once the information is collected, and the forecasts are determined, we provide a clear written analysis of the market conditions. This includes detailed information on market segments regarding market drivers, market restraints, and market opportunities. These offer insights on different channel dynamics, brand preference, incidence/prevalence data, consumption trend, and technology upgradations.

We also include supporting data from relevant awareness campaigns, new introductions, regulatory norms, government initiatives, and an industry player’s expansion in specific product segments. From a research perspective, this information explains and substantiates estimated data finding and forecast which helps us to improve the accuracy of the final report. This helps our clients to make better business decisions as they possess all the market information they require.

Assumptions

  • The report provides the market in terms of USD million/billion at regional as well as country level
  • We have implemented a mixture of top-down and bottom-up approach to estimate the total market and market for an individual segment
  • We reviewed various publications from government and non-government organizations, analyst perspectives for different regions from the paid databases available to us
  • This data helped us extract historical data and market scenario for various countries
  • The total population of respective countries, end users, product demand, local presence of key players, and cost are considered to analyze market revenue
  • Fundamental industry dynamics, demand-supply ratio, and upcoming technological trends are considered for the forecast period.
  • Growth rates are estimated using correlation, regression, and time-series analysis
  • All market estimates and forecasts have been validated through exhaustive primary research with key industry participants and analyst perspectives

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