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Aptamers Market, By Types (Nucleic Acid and Peptide), By Application (Therapeutic, Diagnostics, Research and Development and Others) And Geography (North America, Europe, Asia Pacific, And Rest Of The World) – Analysis, Share, Trends, Size, & Forecast From 2014 – 2025

98 Pages | Published Date : 15 / 11 / 17  | Report Code: AV139 | Report Format: PDF

REPORT HIGHLIGHT

The aptamers market is estimated to represent a global market of USD 668.6 million by 2016 with growth rate of 30.2%.

Market Dynamics

Aptamers are single stranded oligonucleotide or peptide which are engineered through specific selection process to exhibit high binding affinity and specificity to target molecules. Aptamers are synthetic antibodies, designed with comprehensive nucleotide sequence which is generated from in vitro selection process. In most of the cases, aptamers are developed through the Systematic Evolution of Ligands by Exponential Enrichment (SELEX) process. This molecule offer clear cut advantage over antibodies and is projected to grow rapidly in areas such as disease diagnostics and therapeutics. One of the primary driver for the market is that the growing interest of many companies to invest in aptamers industry. It is noticed that companies investigating the potential of aptamers is going up. Number of small companies or start-ups entering in aptamer market is continuously increasing due to its potential advantages compared to the monoclonal antibodies, leading the market growth.

In addition, due to its low manufacturing cost and high specificity and affinity, development of aptamers as diagnostic assay or as nanoparticles for various medical applications provides important opportunity among end users. Research studies are undergoing by various government and non-government bodies to develop novel aptamers for the diverse range of targets such as lipids, carbohydrates, viruses, tissue sections, proteins, organic and inorganic molecules which will expand the scope of aptamers, leading to the market growth. On other side, low awareness coupled with competition with established antibodies market is projected to pull back the market growth to some extent. Also, concern related to failure of clinical studies (for example: Regado Biosciences, Inc. permanently halted enrolment in phase III trial of Revolixys Kit) at late state clinical trials is anticipated to repress the market growth.

Types Takeaway

The global market is divided into Nucleic Acid Aptamers and Peptide Aptamers. Nucleic acid aptamers hold largest share of the total market (over 80% share). Nucleic acid aptamers segment includes variety of DNA aptamer, RNA aptamers and XNA aptamers. DNA aptamers are more stable compared to RNA and XNA aptamers due to the lack of 2-OH group. Further, presence of phosphorothioate backbone increase the bio-stability of DNA based aptamers. Thereby, nucleic acid aptamer are capable of binding with wide range of targets under variety of sample conditions at low cost than antibodies. This advantage helped the nucleic acid aptamer segment to capture significant revenue share of the total market.

Application Takeaway

In terms of application, the market is categorized as Therapeutics, Diagnostics, Research and Developments and Others. Diagnostics segment cover the application of aptamers into molecular imaging techniques, biomarker detection and discovery process. Therapeutics segment is considered to be the most promising market owing to the ability of aptamers’ to develop low cost therapeutics. In 2004, the first aptamer based drugs, Macugen was approved by the U.S. FDA and currently large number of potential aptamer drugs are under clinical investigation.

Currently, large number of research and development actions are going on by multinational or small scale biotechnology companies to unmask the usage of aptamers in various therapeutic applications. For instance, in March 2017, researchers at Mashhad University of Medical Sciences developed aptamers (MUC1 and ATP aptamers) which specifically target murine colon carcinoma cells. This aptamer conjugation offers higher stability and efficient drug loading to target colon cancer cells.

Regional Takeaway

Regionally, developed regions such as North America and Europe capture the large share of the global market. In 2016, North America recorded USD 350.2 million in 2016 and is anticipated to dominate the market over the forecast period. Companies such as Base Pair Biotechnologies, Inc. Ophthotech Corporation and others are domiciled in this region and influence significant presence. Rise in research and development activities on aptamers coupled with growing interest of research laboratories in aptamer field is projected to support the market growth in developed regions. On other side, Asia Pacific region is considered to grow with lucrative growth rate owing to the growing incidence of chronic diseases such as cancer, age related macular degeneration (AMD) and others where aptamer has proven novel therapeutic modality.

Key Vendor Takeaway

Companies such as Opthotech Corporation, Somalogic, Inc., Aptagen, Aptamer Group, NOXXON Pharma and others are considered to be the potential market players of this industry. With the rising concept of aptamer as diagnostics and therapeutics on the horizon, it is noticed that companies investigating the potential of aptamers is going up. Over the past few years, there has been explosive growth in number of research article published in the area of aptamer therapeutics and diagnostics. This number indicates that companies focusing on the aptamers is rising year on year, showing strong potential of the market.

The market size and forecast for each segment has been provided for the period 2014 to 2025, considering 2015 as the base year. The report also provides the compounded annual growth rate (% CAGR) for the forecast period 2016 to 2025 for every reported segment.

The years considered for the study are:

  • Historical Year – 2014 & 2015
  • Base Year – 2015
  • Estimated Year – 2016
  • Projected Year – 2025

TARGET AUDIENCE

  • Traders, Distributors, And Suppliers
  • Manufacturers
  • Hospitals
  • Government and Regional Agencies and Research Organizations
  • Consultants
  • Distributors

SCOPE OF THE REPORT

The scope of this report covers the market by its major segments, which include as follows:

MARKET, BY TYPES

  • Nucleic Acid Aptamers
  • Peptide Aptamers

MARKET, BY APPLICATION

  • Therapeutics
  • Diagnostics
  • Research and Developments
  • Others

MARKET, BY REGION

  • North America
  • Europe
  • Asia Pacific
  • Rest of the World

MARKET, BY COUNTRY

  • Further Breakdown of The North America Market
    • U.S.
    • Canada
  • Further Breakdown of The Europe Market
    • Germany
    • France
    • Rest of Europe
  • Further Breakdown of The APAC Market
    • India
    • China
    • Rest of APAC
  • Further Breakdown of The Rest of the World Market
    • Middle East and Africa
    • Latin America
TABLE OF CONTENT

1. APTAMERS MARKET OVERVIEW
1.1. Study Scope
1.2. Base Year
1.3. Assumption and Methodology
2. EXECUTIVE SUMMARY
2.1. Key Market Facts
2.2. Geographical Scenario
2.3. Companies in the Market
3. APTAMERS KEY MARKET TRENDS
3.1. Market Drivers
3.1.1. Impact Analysis of Market Drivers
3.2. Market Restraints
3.2.1. Impact Analysis of Market Restraints
3.3. Market Opportunities
3.4. Market Future Trends
4. APTAMERS INDUSTRY STUDY
4.1. Company Activity Analysis
4.2. Regulatory Framework Analysis
4.3. Market Attractiveness Analysis
4.4. Value Chain Analysis
5. APTAMERS MARKET LANDSCAPE
5.1. Market Share Analysis
5.2. Key Innovators
6. APTAMERS MARKET – BY TYPES:
6.1. Overview
6.2. Nucleic Acid Aptamers
6.2.1. Overview
6.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
6.3. Peptide Aptamers
6.3.1. Overview
6.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7. APTAMERS MARKET – BY APPLICATION:
7.1. Overview
7.2. Therapeutics
7.2.1. Overview
7.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.3. Diagnostics
7.3.1. Overview
7.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.4. Research and Development
7.4.1. Overview
7.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.5. Others
7.5.1. Overview
7.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8. APTAMERS MARKET– BY GEOGRAPHY
8.1. Introduction
8.2. North America
8.2.1. Overview
8.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.2.3. U.S.
8.2.3.1. Overview
8.2.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.2.4. Canada
8.2.4.1. Overview
8.2.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.3. Europe
8.3.1. Overview
8.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.3.3. France
8.3.3.1. Overview
8.3.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.3.4. Germany
8.3.4.1. Overview
8.3.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.3.5. Rest of Europe
8.3.5.1. Overview
8.3.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.4. Asia Pacific (APAC)
8.4.1. Overview
8.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.4.3. China
8.4.3.1. Overview
8.4.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.4.4. India
8.4.4.1. Overview
8.4.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.4.5. Rest of APAC
8.4.5.1. Overview
8.4.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.5. Rest of the World
8.5.1. Overview
8.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.5.3. Latin America
8.5.3.1. Overview
8.5.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.5.4. Middle East and Africa
8.5.4.1. Overview
8.5.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
9. KEY VENDOR ANALYSIS
9.1. Opthotech Corporation
9.1.1. Company Overview
9.1.2. SWOT Analysis
9.1.3. Key Developments
9.2. Somalogic, Inc.
9.2.1. Company Overview
9.2.2. SWOT Analysis
9.2.3. Key Developments
9.3. Aptagen
9.3.1. Company Overview
9.3.2. SWOT Analysis
9.3.3. Key Developments
9.4. Aptamer Group
9.4.1. Company Overview
9.4.2. SWOT Analysis
9.4.3. Key Developments
9.5. NOXXON Pharma
9.5.1. Company Overview
9.5.2. SWOT Analysis
9.5.3. Key Developments
10. 360 DEGREE ANALYSTVIEW
11. APPENDIX
11.1. Research Methodology
11.2. Abbreviations
11.3. Disclaimer
11.4. Contact Us

List of Tables
Table 1 List of Acronyms
Table 2 Key Market Facts, 2014 – 2025
Table 3 Market Drivers: Impact Analysis
Table 4 Market Restraint: Impact Analysis
Table 5 Market Opportunity: Impact Analysis
Table 6 PESTLE Analysis
Table 7 Porter’s Five Forces Analysis
Table 8 Company Market Share Analysis
Table 9 Global Aptamers Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
Table 10 Aptamers Market, by Types, 2014 – 2025 (USD Million)
Table 11 Aptamers Market, by Application, 2014 – 2025 (USD Million)
Table 12 Aptamers Market, by Geography, 2014 – 2025 (USD Million)
Table 13 North America Aptamers Market, 2014 – 2025 (USD Million)
Table 14 U.S. Aptamers Market, 2014 – 2025 (USD Million)
Table 15 Canada Aptamers Market, 2014 – 2025 (USD Million)
Table 16 Europe Aptamers Market, 2014 – 2025 (USD Million)
Table 17 France Aptamers Market, 2014 – 2025 (USD Million)
Table 18 Germany Aptamers Market, 2014 – 2025 (USD Million)
Table 19 Asia Pacific Aptamers Market, 2014 – 2025 (USD Million)
Table 20 China Aptamers Market, 2014 – 2025 (USD Million)
Table 21 India Aptamers Market, 2014 – 2025 (USD Million)
Table 22 Latin America Aptamers Market, 2014 – 2025 (USD Million)
Table 23 MEA Aptamers Market, 2014 – 2025 (USD Million)

List of Figures
Figure 1 Research Methdology
Figure 2 Research Process Flow Chart
Figure 3 Comparative Analysis, by Geography, 2016-2025 (Value %)
Figure 4 Regulatory Framework Analysis
Figure 5 Value Chain Analysis Analysis
Figure 6 Aptamers Market, by Types, 2014 – 2025 (USD Million)
Figure 7 Aptamers Market, by Application, 2014 – 2025 (USD Million)
Figure 8 Aptamers Market, by Geography, 2014 – 2025 (USD Million)

SCOPE AND OBJECTIVES :
The objective of this report is to describe the market trends and revenue forecasts for the market for the upcoming years. The report focuses on defining and describing the key influencing factors for the growth of the market. It also offers an in-depth analysis of the market size (revenue), market share, major market segments, different geographic regions, key market players, and premium industry trends.
The report tracks the major market events including product launches, technological developments, mergers & acquisitions, and the innovative business strategies opted by key market players. Along with strategically analysing the key micro markets, the report also focuses on industry-specific drivers, restraints, opportunities and challenges in the market. The scope of this report covers the market by its major segments, which include the source, disease end user industry, and the major geographic regions.

KEY BENEFITS OF THE REPORT :
• Understanding of the strategies that are being adopted by the key players in this market to stay competitive
• Extensive analysis of the key players dominating the competitive landscape of this market
• In-depth analysis of the key factors are propelling the growth of the global market
• Detailed analysis of the geographic region that will witness the strongest growth
• Granular analysis of the current market scenario and the expected market grow

RESEARCH METHDOLOGY

AnalystView’s research methodology is developed on a combination of specialist industry analyst knowledge and in-country research experience. We employ data interrogation methodologies to generate new and meaningful analyses and insights. The research study involves extensive usage of secondary sources, directories, and databases (such as Hoovers, Bloomberg, and Businessweek) to identify and collect information useful to understand technical, market-oriented, and commercial aspects of market. Market data and information are also collected and not limited to secondary sources like:

  • Official Company’s Website, Financial and Annual Reporting
  • Government Statistical Data
  • Online Publishing Articles
  • Industry Player’s Investor Presentations
  • Economic News Articles
  • National and International Trade Associations
  • The Financial, Business and Mainstream Press
  • Industry Study Groups and Other Semi-Official Sources
  • Many Other Informative Channels Related to the Market Topics

Gathering data through secondary sources is only the first step. The ability to cross-refer market data through available secondary information often conflicting across multiple sources is a key aspect of the added value we provide

In order to verify and validate secondary market data, we engage with a variety of personnel in key players at all points through phone calls, emails and web based survey responses with key opinion leaders (KoL’s) operating in the respective markets. The engagement involves the CEO, vice presidents, top-level and middle-level managers of the company, directors of marketing, product managers, brand managers, customers of major industrial products, and many others. We also interview manufacturers, distributors, materials suppliers, retailers, service operators, study groups, industry associations, and third party observers from the trade and financial press. These obtained information helped us to understand several facets of the market with respect to manufacturers’ and buyers’ perspective. These data were carefully filtered, analyzed, compared and presented in an easy way to develop accurate research study. Furthermore, all collected data is subjected to undergo exhaustive review process at country level, regional level and global level.

MARKET FORECAST

Market forecast for the respective market is primarily based on the year on year (YOY) growth rate. Data projection and future performance of each segment analyzed based on the key aspects extracted from primary and secondary research results. Thus data projection states the assumption on how the market behaves under macroeconomic and microeconomic parameters. Our market forecasting represents strategic conclusion we have reached about the coming state of the market scenario.

 MARKET ANALYSIS

Another integral part of our research study is that AnalystView’s market data is accompanied by clear written analysis. We include detail information on market segments in terms of market drivers, market restraints and market opportunities. These offer insights of different channel dynamics, brand preference, incidence/prevalence data, technology up gradation, consumption trend, and future market scenario. We also include supporting data with any relevant awareness campaign, new introduction, regulatory norms, government initiatives, and industry player’s expansion in specific product segments. From research perspective, this information explains and substantiates estimated data finding and forecast.

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