Aptamers Market Size Worth $9.1 Billion By 2025 | CAGR: 30.2%
Published Date : 15 / 12 / 17 | Report Format: PDF
The global aptamers market is expected to grow at growth rate of 30.2% to reach USD 9,125.6 million by 2025.
Aptamers are short single stranded oligonucleotide and peptides that enable to bind with the target molecule with high specificity and affinity. Aptamers are selected through in vitro procedure, based on affinity towards the target molecule, which can be a virus, protein, or cell. Systematic Evolution of Ligands by Exponential enrichment (SELEX) is primarily utilized iterative enrichment technique to identify quality aptamers. Factors such as increasing demand for cost effective therapeutics, rising research and development activities, increasing number of companies coupled with advantages over antibodies support the market growth to great extent. Furthermore, increasing number of aptamers under late stage clinical trials boost the market scope.
Currently, around ten aptamers are under distinct phases of clinical studies for the treatment of neo-vascular macular degeneration (company: Ophthotech), coronary artery disease (company: Regado Bioscience), von Willebrand’s disease (company: Archemix Corporation), type II diabetes mellitus (company: Noxxon Pharma), and others. However, major limitations of aptamers include its rapid clearance rate from the circulation owing to its small molecular size and nuclease degradation. This factor would in turn catch up antibodies over the aptamers utilization among end users.
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The global market is divided into Nucleic Acid Aptamers (DNA, RNA and XNA) and Peptide Aptamers. Nucleic acid aptamers hold largest share of the total market (over 80% share). Peptide aptamers represent new class of molecules with broad potential in biomedical field. Introduction of novel peptide aptamers by key companies is expected to establish healthy platform for the growth of this market. For example, Aptagen, LLC offers Peptimers, peptide based aptamer.
In terms of application, the market is categorized as Therapeutics, Diagnostics, Research and Developments and Others. Research and development application captured more than USD 1.5 billion in 2016 and is considered to grow with the significant growth rate over the future period. The recent outbreak of Zika Virus in Brazil and the U.S. has opened new opportunity for aptamers. Pennsylvania based Aptamer Group, leading player of the market, suggested that the reliance of Zika (MAC-ELISA) virus on antibodies is presents a strong platform for the aptamers to enter the market due to its high affinity and specificity. Many research studies also suggested that it is possible to devise biosensor like diagnostic platform through aptamers to fight Zika virus. These would in turn establish the healthy platform for the market to grow globally.
Key Takeaways :
► With the rising concept of aptamer as diagnostics and therapeutics on the horizon, it is noticed that companies investigating the potential of aptamers is going up. Over the past few years, there has been explosive growth in number of research article published in the area of aptamer therapeutics and diagnostics. This number indicates that companies focusing on the aptamers is rising year on year, showing strong potential of the market.
► Regionally, developed regions such as North America and Europe capture the large share of the global market
► In 2016, North America recorded USD 350.2 million in 2016 and is anticipated to dominate the market over the forecast period. Companies such as Base Pair Biotechnologies, Inc. Ophthotech Corporation and others are domiciled in this region and influence significant presence.
► Rise in research and development activities on aptamers coupled with growing interest of research laboratories in aptamer field is projected to support the market growth in developed regions
► On other side, Asia Pacific region is considered to grow with lucrative growth rate owing to the growing incidence of chronic diseases such as cancer, age related macular degeneration (AMD) and others where aptamer has proven novel therapeutic modality
► Companies such as Opthotech Corporation, Somalogic, Inc., Aptagen, Aptamer Group, NOXXON Pharma and others are considered to be the potential market players of this industry.
KEY BENEFITS OF THE REPORT :
- In-depth analysis of the key factors are propelling the growth of the global market
- Granular analysis of the current market scenario and the expected market grow
- Detailed analysis of the geographic region that will witness the strongest growth
- Understanding of the strategies that are being adopted by the key players in this market to stay competitive
- Extensive analysis of the key players dominating the competitive landscape of this market
The scope of this report covers the market by its major segments, which include as follows:
Market Segmentation :
APTAMER MARKET,BY TYPES
- Nucleic Acid Aptamers
- Peptide Aptamers
APTAMER MARKET,BY APPLICATION
- Research and Development
APTAMER MARKET, BY REGION
- North America
- Asia Pacific
- Rest of the World
APTAMER MARKET, BY COUNTRY
- North America Market
- Europe Market
- Rest of Europe
- APAC Market
- Rest of APAC
- The Rest of the World Market
- Middle East and Africa
- Latin America
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